Grushin
Research group
Abstract
Our research spans organic and inorganic chemistry with emphasis on metal complex catalysis and mechanistic studies. The main focus of the group is on new chemical transformations toward the development of highly challenging and practicable processes as well as deep understanding of elementary steps involved in the catalytic loop. Many of our projects are centered on organometallic fluorine chemistry, a new and exciting area for research. Our ultimate goal is the development of efficient methods for highly chemo- and regioselective, practicable fluorination, trifluoromethylation, and fluoroalkylation reactions of organic molecules with metal reagents and catalysts. Our other research interests include the synthesis of homogeneous catalysts, fine chemicals from renewable resources, inert bond activation, and new metal-catalyzed reactions of otherwise unreactive aromatic substrates.
Topics addressed
- Organometallic fluorine chemistry
- New, Highly Efficient, Simple, Safe, and Scalable Synthesis of [(Ph3P)3Ru(CO)(H)2]
Articles
“Distinct Mechanism of Oxidative Trifluoromethylation with a Well-Defined Cu(II) Fluoride Promoter: Hidden Catalysis”
J. Am. Chem. Soc. 2014,135, 136, 16998-17001
N. Nebra, V. V. Grushin
“On the Feasibility of Nickel-Catalyzed Trifluoromethylation of Aryl Halides”
Organometallics 2014, 52, 33, 6531-6543
J. Jover, F. M. Miloserdov, J. Benet-Buchholz, V. V. Grushin, F. Maseras
“Alcoholysis of Fluoroform”
Journal of Fluorine Chemistry 2014, 167, 105-109
F. M. Miloserdov, V. V. Grushin
“Mechanism of Trifluoromethylation of Aryl Halides with CuCF3 and the Ortho Effect”
J. Am. Chem. Soc. 2014, 136, 13410-13425
A. I. Konovalov, A. Lishchynskyi, V. V. Grushin
“Trifluoromethylation of Arenediazonium Salts with Fluoroform-derived CuCF3 in Aqueous Media”
Chem. Commun. 2014, 50, 10237-10240
A. Lishchynskyi, G. Berthon, V. V. Grushin
“Continuous Process for Production of CuCF3 via Direct Cupration of Fluoroform”
Org. Process. Res. Dev. 2014, 18, 1020-1026
Z. Mazloomi, A. Bansode, P. Benavente, A. Lishchynskyi, A. Urakawa, V. V. Grushin
“Fluoroform as a Feedstock for High-value Fluorochemicals: Novel Trends and Recent Developments”
Chim. Oggi Chem. Today 2014, 32, 81-90
V. V. Grushin
“The Challenge of Palladium-Catalyzed Aromatic Azidocarbonylation: From Mechanistic and Catalyst Deactivation Studies to a Highly Efficient Process”
Organometallics 2014, 33, 736–752
F. M. Miloserdov, C. L. McMullin, M. Martínez Belmonte, J. Benet-Buchholz, V. I. Bakhmutov, S. A. Macgregor,V. V. Grushin