High Throughput Experimentation CELLEX-ICIQ Laboratory
THE UNIT IN 2014
The High Throughput Experimentation (HTE) laboratory is a facility that makes accessible to all ICIQ researchers the instrumentation and know-how to run a large number of reactions and analyze them in a short period of time.
The facility is prepared to run different kind of reactions in 24 or 96 well plates, including those that are air sensitive, reactions with reactive gases, photochemical reactions or reactions under pressure conditions. Moreover, the Laboratory is stocked with a large number of reagents, solvents, metals and ligands to run the reactions.
Regarding the analysis of the reactions, the lab is equipped with an NMR spectrometer and three chromatographs: a GC-MS, a UHPLC-MS and a supercritical CO2 chromatograph with diode array or MS detector.
To speed up the run processes, the lab is also equipped with specific software to prepare the experiments and analyze the results coming from the chromatographs.
This Unit started its activities on June 2014 and until the end of the year, 89 screening experiments were adapted to HTE working conditions, run and analysed.
MOST IMPORTANT EQUIPMENT
- 300 MHz NMR Spectrometer from Bruker®
- GC-MS from Agilent Technologies®
- Glove Box train from MBraun®
- Parallel Centrifugal Evaporator from Genevac®
- Pressure reactors
- SFC chromatograph from Waters®
- Tumble stirrers
- UHPLC-MS chromatograph from Waters®
- Well plates